“Lowering proteinuria is paramount to prevent kidney damage and avert progression to renal failure in IgA nephropathy patients”
Professor Raphael Duivenvoorden
Nephrologist
Discover the role of PROTEINURIA in glomerular disease
Proteinuria is a key marker and predictor of disease progression in IgAN1–6
Understand IgAN and its impact on kidney function
IgAN is characterized by a progressive loss of kidney function leading to end-stage kidney disease (ESKD), which profoundly impact patients' quality of life (QoL)7,8
Uncover the DUAL Pathway driving disease progression in IgAN
Endothelin-1 (ET-1) and angiotensin II (ANG II) both play fundamental roles in the pathophysiology of kidney diseases9–12
The KDIGO Guidelines
The 2025 KDIGO guideline for management of IgAN and IgA vasculitis updated treatment goals and recommendations for IgAN patients
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