Proteinuria is a key marker of prognosis and disease severity in IgAN2,5,9,10

Proteinuria and reduced estimated glomerular filtration rate (eGFR) are joint contributors to glomerular disease progression2,5

Proteinuria icon

Kidney function in IgAN

High proteinuria and declining eGFR are associated with an increased risk of disease progression in IgAN2,3

Slower decline in kidney function

Higher proteinuria levels are associated with a faster decline in eGFR;3,5 conversely, patients within normal proteinuria levels show a slower decline in eGFR2

Increased proteinuria was a stronger predictor of disease progression than a reduced eGFR2

Target proteinuria to slow progression to kidney failure